Estrogen management is the most controversial topic in the testosterone replacement therapy community. One of the reasons for this controversy is the medicines used to manage estrogen levels in men, Aromatase Inhibitors like Arimidex. Arimidex has been clinically shown to lower bone density and have a negative impact on lipid profiles.
We created No AI to give men who have negative side effects from higher estrogen levels something to help manage their estrogen levels naturally with ingredients that may offer some health benefits as well!
We have combined five clinically proven estrogen management supplements into one powerful supplement. No AI! This the first supplement on the market to combine five estrogen fighting supplements at full clinical dosages!
Diindolylmethane (DIM) - 400mg
DIM is well known in the TRT community and is probably the most widely used estrogen management supplement taken by guys on TRT who are looking to manage their estrogen levels without the use of an AI.
DIM is found naturally in many cruciferous vegetables like Broccoli, Cabbage, Brussel Sprouts and Cauliflower. You would need to eat two pounds of broccoli to get 20mg of DIM.
DIM does not actually block testosterone conversion to estrogen. DIM is believed to speed up your bodies natural metabolism for estrogen.
Some research shows DIM increases the level of "favorable" estrogens (2-hydroxyestrogen) while reducing the level of "less favorable" estrogens (16-hydroxyestrogen).
DIM Possible Health Benefits
Helps prevent the effects of estrogen on cells
Slows some cancer cells
Lowers toxins produced by your body’s natural metabolism
Promotes weight loss
Supports cardiovascular health
Promotes good muscle development
Improves prostate health for men
Calcium D-Glucarate - 1,000mg
Calcium D-Glucarate is the salt and the commercial form of glucaric acid, which occurs naturally in a variety of foods including apples, oranges, broccoli, and spinach.
Calcium D-Glucarate has been shown to help speed up the process of removing toxins in the body. In one study, calcium-d-glucarate was able to reduce the number of estrogen receptors by 48 percent. It’s also been shown to lower serum estrogen levels by 23 percent.
It has also been shown to reduce LDL levels which is of concern if you are on TRT as testosterone has been shown to raise LDL levels.
Calcium D-Glucarate Possible Health Benefits
Supports liver detoxification
Potentially inhibits some types of cancer
Helps maintain already healthy cholesterol levels
Indole-3-Carbinol (I3C) - 400mg
Indole-3-carbinol is formed from a substance called glucobrassicin found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas. I3C actually breaks down into DIM in the body, but not before helping to reduce estrogen and possibly having anti cancer properties.
I3C has been shown to improve Phase I detoxification of estrogens favoring the less potent 2OH estrone pathway.
I3C has been shown to exhibit potent anticarcinogenic properties in a wide range of cancers such as lung, liver, colon, cervical, endometrial, prostate, and breast cancer.
Grape Seed Extract (Vitas Vinifera) - 195mg
Grape Seed Extract is exactly what its name suggests. It's basically ground up grape seeds. Grape seed extract (GSE) contains high levels of procyanidin dimers that have been shown to be potent inhibitors of aromatase. In one study, GSE was found to inhibit aromatase activity in a dose-dependent manner.
Grape Seed Extract Possible Health Benefits
Reduce blood pressure
Improve blood flow
Reduce oxidative damage
Improve collagen levels and bone strength
Improve kidney function
Protect your liver
Enhance wound healing
Bioperine® Black Pepper (Piper Nigrum) - 5mg
Bioperine® is a patented highly concentrated Black Pepper extract containing at least 95% piperine in a form that is well absorbed by your body. It has also been shown to increase the bioavailability of many natural compounds. It is also a powerful antioxidant and has exhibited many health benefits. They patented this stuff for a reason!